Written by Jianping Liu, Xun Li and the CAM-Cancer Consortium.
Updated April 12, 2010

Green tea (Camellia sinensis)

Abstract and key points

  • Green tea is (like black tea) derived from the schrub Camellia Sinensis but through a non-fermenting process.
  • The evidence for an association between green tea consumption and the incidence of cancer is generally inconsistent.
  • Drinking green tea appears safe at regular, habitual and moderate use.

Green tea is derived from the shrub Camellia sinensis, the same plant as used for black tea, but is not fermented.

A 2009 Cochrane review of 51 randomized clinical trials, observational studies and case-control studies with over 1.6 mio participants concluded that there is insufficient and conflicting evidence to establish an association between green tea consumption and the incidence of cancer.1

One earlier systematic review including 43 epidemiological studies, 4 randomized trials and 1 meta-analysis with the overall quality as good or moderate found that some evidence suggested that green tea might have beneficial effects on gastrointestinal cancers, but the findings were not consistent.2

Four other systematic reviews on the risk association between green tea and lung cancer3, breast cancer4, colorectal cancer5 and stomach cancer6 respectively found inverse association between green tea consumption and cancer incidence but the studies were generally associated with heterogeneity.

Although the majority of the studies show that long-term consumption of large amounts of green tea may prevent the occurrence of some forms of cancer, the findings of both cohort studies and case-control studies are inconsistent.

Drinking green tea appears safe at regular, habitual and moderate use (3-9 cups per day).

Citation Jianping Liu, Xun Li , CAM-Cancer Consortium. Green tea (Camellia sinensis) [online document]. http://www.cam-cancer.org/CAM-Summaries/Herbal-products/Green-tea-Camellia-sinensis. April 12, 2010.

References

  1. Boehm K, Borrelli F, Ernst E, Habacher G, Hung SK, Milazzo S, Horneber M. Green tea (Camellia sinensis) for the prevention of cancer. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.: CD005004. DOI: 10.1002/14651858.CD005004.pub2.
  2. Liu J, Xing J, Fei Y. Green tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies. Chin Med. 2008 Oct 22;3:12.
  3. Tang N, Wu Y, Zhou B, Wang B, Yu R. Green tea, black tea consumption and risk of lung cancer: a meta-analysis. Lung Cancer. 2009; 65: 274-83.
  4. Ogunleye AA, Xue F, Michels KB. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat. 2009 May 13. [Epub ahead of print]
  5. Sun CL, Yuan JM, Koh WP, Yu MC. Green tea, black tea and colorectal cancer risk: a meta-analysis of epidemiologic studies. Carcinogenesis 2006; 27: 1301-9.
  6. Myung SK, Bae WK, Oh SM, Kim Y, Ju W, Sung J, Lee YJ, Ko JA, Song JI, Choi HJ. Green tea consumption and risk of stomach cancer: a meta-analysis of epidemiologic studies. Int J Cancer 2009; 124: 670-7.
  7. Anonymous. Green tea detailed scientific review. The University of Texas MD Anderson Cancer Center. http://www.mdanderson.org/departments/cimer/ accessed Oct 11, 2009.
  8. Brown MD. Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer. Altern Med Rev 1999;4:360-70.
  9. The Natural Medicines Comprehensive Database. http://www.naturaldatabase.com/ accessed Oct 11, 2009.
  10. Sarma DN, Barrett ML, Chavez ML, Gardiner P, Ko R, Mahady GB, Marles RJ, Pellicore LS, Giancaspro GI, Low Dog T. Safety of green tea extracts : a systematic review by the US Pharmacopeia. Drug Saf. 2008;31(6):469-84.
  11. Fujiki H, Suganuma M, Okabe S, Sueoka E, Suga K, Imai K, Nakachi K, Kimura S. Mechanistic findings of green tea as cancer preventive for humans. Proc Soc Exp Biol Med 1999;220:225-8.